Prior to starting a detoxification program it is important to achieve optimal bowel function.* It is therefore important to include a fiber formula, such as Thorne's FiberMend®, to support the elimination of toxins from the body by binding the toxins released into the intestines from the liver and preventing their reabsorption.*
The liver employs a two-phase method of detoxification. In phase I, fat-soluble substances, including toxins, are converted by the cytochrome p450 enzymes into intermediate substances that, while they are now more water-soluble, are not yet ready to be eliminated. Then, in phase II, the intermediate substances created during phase I are attached to glutathione, sulfur, or methyl groups that make them sufficiently water-soluble so as to be excreted from the liver in the bile.*
The suggested starting use of Liver Cleanse is to take one capsule in the evening. If additional liver cleansing is indicated, then supplementation can be gradually increased.
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